Alzheimer is a chronic condition that causes pain in the muscle and soft tissue of the body. The pain may fluctuate with time of day, physical activity, weather, or stress 

Experiencing pain after surgery is normal and is often due to inflammation in the part of the body where surgery occurred. ​This type of pain is called acute post-surgical pain and is short-term, generally less than three months.​ However, 5-10% of patients who undergo major surgery develop chronic post-surgical pain, which is pain that persists past the normal healing process (generally longer than three months).   

Fibromyalgia is a medical condition that is believed to affect the central nervous system. The most common symptom of fibromyalgia is chronic musculoskeletal widespread pain.

Sickle cell disease (SCD) is a genetic condition that causes red blood cells to become abnormally shaped. When their shape is abnormal, red blood cells have a more difficult time moving through blood vessels and carry oxygen. This can cause pain and other health problems. People with sickle cell disease may experience episodes of severe pain, fatigue, and organ damage. The disease is most common among people of African, Mediterranean, and Middle Eastern descent.